The 7 Best Nootropics for Quitting Weed Addiction

 Weed, or marijuana, is one of the most used federally illegal drugs in America. As more American states legalize marijuana, the more accessible marijuana is to those in the United States who wish to smoke it, including underage individuals. Occasionally, using marijuana can develop into a dependency that does not just affect the addict, but also the entire family. Marijuana Use Disorder affects at least 30% of the population that use marijuana. In severe cases, Marijuana Use Disorder can lead to addiction. Statistics mentioned on the National Institute on Drug Abuse (NIDA) website claim individuals who start to use marijuana before the age of 18 are four to seven times more likely to develop an addiction to marijuana in the future, compared to individuals who started to use marijuana as adults. New studies show that there are benefits to using nootropics to quit weed addiction and to reduce the symptoms of weed withdrawal.


Using Nootropics for Weed Addiction

Marijuana use disorders develop when an individual starts to feel withdrawal symptoms. Irritability, difficulty sleeping, a decrease in hunger, brain fog, and food cravings are all common symptoms of weed withdrawal. Nootropics can help mitigate these negative symptoms to make quitting weed much easier. The feelings of withdrawal may result in individuals deciding not to quit. Due to the negative symptoms of withdrawal, some studies have been conducted to discover if there’s a substance that would help ease withdrawal symptoms for those who want to quit using marijuana. Nootropics – also known as smart drugs – are a group of over the counter dietary supplements that have been shown to increase brain function and reduce withdrawal symptoms among other benefits. Nootropics are generally designed to improve cognitive function but have other benefits for those who choose to take them. These substances have been shown to reduce depression, anxiety, lack of focus, insomnia, restlessness as well as improve cognitive function, working memory, and reduce the symptoms of common brain-related disorders such as ADHD and dementia. Pharmacotherapies to help combat substance addiction have been a topic of great interest to many organizations, and scientists for years. Nootropics such as NAC (N. Acetylcysteine), Caffeine + L-Theanine, Rhodiola Rosea, Piracetam, GABA, and Phenibut have been mentioned in many studies that conclude these supplements have many benefits for those who want to use nootropics for weed addiction.


NAC (N. Acetylcystiene) for Quitting Weed

The effects of taking NAC (N. Acetylcysteine) to ease withdrawal symptoms of weed (and nicotine) addiction have shown great promise in the scientific community. NAC has been used to treat patients who overdosed on acetaminophen (over the counter pain medications) due to its antioxidant qualities that reduce the function of the neurotransmitter glutamate. When glutamate is not regulated properly, substance abuse relapse is more likely to occur.

The effects of taking NAC (N. Acetylcysteine) to ease withdrawal symptoms have shown promise in the scientific community. NAC has been used to treat patients who overdosed on acetaminophens (over the counter pain medication) due to its antioxidant qualities that reduce the function of the neurotransmitter glutamate. When glutamate isn’t regulated at a healthy level, substance abuse relapse is more likely to occur.

A series of controlled studies designed to test the effectiveness of NAC on marijuana, cocaine, and methamphetamine addicts, concluded NAC helps addicts by reducing withdrawal symptoms. 24 participants within the age range 18-21 years old who were addicted to marijuana, were given specific amounts of NAC. Twice a day, this age group was administered 1200mg of NAC for a month. Those that took the 1200mg NAC prescription for 4 weeks reported suffering fewer cravings and a reduction in the number of times they used marijuana per day. In the next experiment, 116 cannabis dependent participants in the age range of 15- 21 years were tested to determine the effects of NAC on marijuana substance use. The participants were given 1200mg of NAC twice a day for 8 weeks and compared to the placebo (control group). The results of this test were the same as the first; participants reported fewer marijuana cravings and ended us using marijuana less frequently. 

The overall conclusion from this study showed that NAC was successful in reducing marijuana cravings in marijuana dependent individuals.

If you’re addicted to weed and would like to use nootropics to quit weed, then using NAC, or N-acetylcysteine, is a great nootropic to take, especially if you have trouble giving into cravings. Although side effects of NAC are incredibly rare, at high dosages, some individuals have reportedly experienced drowsiness, clamminess, stomatitis, rhinorrhea, and hemoptysis. Always consult your doctor for medical advice.

L -Theanine and Caffeine for Quitting Weed

Combined, L-Theanine and Caffeine reduce anxiety and stress especially in those who are trying to quit substance abuse. L-Theanine is extracted from green tea leaves, which are commonly steeped into a tea known for its relaxing benefits. Caffeine, commonly found in America’s most popular drink, coffee, is a psychoactive substance that stimulates the brain’s adenosine receptors. Interestingly, one study showed that humans who took caffeine and L-theanine together before bed saw even better results compared to those who took l-theanine and caffeine when they were just waking up or during the day.

L-Theanine, a natural amino acid,  is touted as one of the safest and most effective nootropics available. L-Theanine induces a state of relaxation and reduced anxiety without inducing drowsiness. It is commonly taken in conjunction with caffeine to boost energy and alertness but is still very effective when taken on its own. There are no known side effects associated with the use of L-Theanine.

L-Theanine and Caffeine are two of the best nootropics for quitting weed addiction, especially when taken together. 

Rhodiola Rosea for Quitting Weed

Rhodiola Rosea has been used for centuries as a natural medicine in parts of Eurasian culture. The use of Rhodiola Rosea has benefited people who suffer from stress, anxiety, depression, and other health conditions. It can also help reduce mental and physical fatigue and increase endurance. In addition to these great benefits, Rhodiola Rosea has been reported to significantly decrease hunger and food cravings. In one study, 60 adults aged 22 to 50 years old who suffered from Chronic Fatigue Syndrome (CFS) were selected to participate in a study to test whether Rhodiola Rosea could increase the amount of energy presented in these adults. Two groups were formed out of the 60 participants. 30 participants were given a placebo pill, and the other 30 participants were given 576mg of Rhodiola Rosea extract in a tablet.

The results of the experiment showed that Rhodiola Rosea significantly reduced fatigue in both groups, with the much higher improvement shown in the patients that were prescribed the Rhodiola Rosea pill.

Fatigue is a common side effect of marijuana withdrawal, something Rhodiola Rosea is clinically proven to help with. This makes Rhodiola Rosea a great nootropic for quitting weed and dealing with weed withdrawal symptoms.


Piracetam for Quitting Weed Addiction

Cannabis use has been directly linked to memory and learning impairment. To measure the effects of learning impairment due to cannabis and the potential benefits Piracetam might have, a study was conducted where Piracetam and cannabis were administered to mice. After administering the drugs, the mice were placed in a maze. Scientists then measured the time it took for the mice to complete the maze. Mice that were treated with Piracetam took significantly less time to escape the maze compared to mice that were either in the control group or were only administered cannabis. Piracetam is an excellent nootropic for weed addiction that is recommended due to its cognitive benefits. Benefits of Piracetam include increased brain function, reduced inflammation, and enhanced memory. We have tested and ranked several different brands of Piracetam, and recommend Pure Nootropics Piracetam as the number one brand of Piracetam available online.

Ashwagandha for Quitting Your Weed Addiction

Ashwagandha is an herb commonly used as a nootropic substance to induce a state of relaxation and reduce anxiety. Some additional research has been done on ashwagandha to study its potential anti-tumor and anti-inflammatory properties. Many people who use ashwagandha report overall mood improvement and an enhanced state of relaxation. This makes it an excellent nootropic for quitting a weed addiction since its benefits can help replace the anxiety-reducing and relaxing effects of marijuana use in a healthy way. We recommend using what is known as “KSM-66 Ashwagandha extract” as it is the safest and highest quality ashwagandha extract available. You can purchase ashwagandha from Nootropics Depot or Pure Nootropics, the two most reliable and safe nootropics suppliers on the internet.

Using GABA Supplements for Weed Addiction

GABA supplements are a relatively untested group of nootropics for weed addiction in terms of direct effects on weed addicted users, however, there is a strong link bewteen the neurotransmitter GABA and less anxiety and depression. Medications that block GABA production, such as gabapentin, are prescribed to patients with bipolar disorder and schizophrenia and work by blocking GABA transports. A study conducted by Joshua A. Lile and colleagues aimed to examine the potential benefits that a GABA increasing nootropic could have on individuals suffering from substance abuse disorders. The nootropic used in this experiment is called tiagabine. Tiagabine is a neurotransmitter reuptake inhibitor that decreases the production of GABA. Lile and colleagues were able to successfully recruit 8 qualifying participants from a community to undergo this experiment. The 8 participants were given a tablet that might contain nothing but cornstarch, THC and tiagabine, and just THC or just tiagabine. When sampling the drugs, each letter on a drug was assigned to a person. When sampling, participants were tasked with taking 4 pills with different side effects. These sampling sessions occurred twice a day Monday through Friday, and the procedure lasted for 7 and a half hours. At the end of the experiment, Lile et. al. concluded tiagabine should be considered a viable treatment for substance abuse disorders. GABA supplements are taken orally, and there has been no observed increase in depressive behavior from these dosages, however, very large doses may lead to depression. One common GABA modulating supplement is Phenibut:


Phenibut is a drug that has been around since the 1960s. It acts as an anxiolytic (anxiety-reducer) by attaching to GABA-receptors in the brain. The drug was created in the soviet union to increase the mental capacity of its users. Today, Phenibut can be used to decrease common cannabis withdrawal symptoms such as anxiety, depression, and fatigue. Phenibut is commonly used for treating and reducing anxiety, fear, insomnia, tension, fatigue, post-PTSD, depression, and alcoholism. It is also used for enhancing learning, improving memory, and increasing cognitive function. 

Phenibut is legal in the United States and can easily be purchased online from trusted nootropics retailers such as Nootropics Depot and Pure Nootropics. It can be used to treat anxiety, depression, and other mental health disorders. Phenibut is considered a nootropic due to its ability to increase cognition. Always seek the advice of a medical professional if you are considering using Phenibut as a nootropic to quit weed addiction.

Effects of Weed Use and Dangers Presented

 When a person is under the influence of marijuana, they will likely experience short term physical and mental effects including sensory impairment, an altered sense of time, mood alterations, impaired movement, difficulties in cognitive functioning, memory impairment, delusions, and hallucinations when weed is taken at a high dose. Long term effects of marijuana use include trouble breathing, an increased heart rate, child development problems in and after pregnancy, and nausea. Hallucinations and delusions have been reported by those who smoked weed for a long time and have a history of mental illness. Those who smoke marijuana early in their life can develop a decrease in cognitive function, losing up to 4 IQ points later in life compared to those who did not smoke weed in their adolescence.

Short term effects of cannabis use can impair drivers who are under the influence of weed. This is a reason that many states that legalize marijuana in America make driving under the influence of marijuana illegal. After long term use, withdrawal symptoms tend to occur and present themselves similar to withdrawal symptoms of benzodiazepines.

Signs of Weed Addiction

Determining if someone is addicted to marijuana can be difficult. Often, an addict will want to quit using the substance, but can’t seem to stop due to feelings accompanying withdrawal. Individuals who experience a decrease in appetite, irritability, trouble sleeping, and restlessness are most likely dependent on marijuana.


Overall, the benefits of nootropics are being explored in scientific studies. Although studies suggest potential benefits to using nootropics, side effects have been observed within the occasional person at high dosages. Using nootropics for weed withdrawal can be a great way to ease common symptoms. In conclusion, quitting weed with nootropics is a low-risk solution to those who are having a hard time stopping their use of marijuana because of the symptoms of withdrawal.


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